
What are Polynucleotides?
Polynucleotides are DNA fractions which have been extracted from the sperm of either salmon or trout. When purified and injected in to specific areas of the face, polynucleotides assist with the hydration of ageing skin by attracting water molecules.Â
Benefits:
- Act as wound healing agents for scar tissue and skin imperfections
- Boost cell renewal with antioxidant properties
- Reduce inflammation
- Restore youthful volume and hydration
- Promote smoother, brighter, and healthier skin over time

WHERE DO WE USE POLYNUCLEOTIDES?

NEWEST

PLINEST

PLINEST (eye)

PLINEST (hair)
Prices and Booking
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Polynucleotides by Mastelli for Skin and/or Hair + Bio Synthesis LED Light Therapy £285
This is the cost of a single session for one area. We recommend: for skin -3-4 sessions at 3 weeks interval and 1 treatment for maintenance every 6 months and for hair 4 sessions every 1-2 weeks and after that, one treatment every 3 weeks for an additional four sessions.
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Course of 3 treatments for one area: Polynucleotides by Mastelli for Skin and/or Hair + Bio Synthesis LED Light Therapy £750
This is the cost of a three sessions for one area. We recommend: for skin -3-4 sessions at 3 weeks interval and 1 treatment for maintenance every 6 months and for hair 4 sessions every 1-2 weeks and after that, one treatment every 3 weeks for an additional four sessions.
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Course of 3 treatments for two areas: Polynucleotides by Mastelli for Skin and/or Hair + Bio Synthesis LED Light Therapy £1250
This is the cost of three sessions for any two areas. We recommend: for skin -3-4 sessions at 3 weeks interval and 1 treatment for maintenance every 6 months and for hair 4 sessions every 1-2 weeks and after that, one treatment every 3 weeks for an additional four sessions.
Frequently Asked Questions
What is the consultation process like?
We believe in a personalized approach. Prior to treatment, you will be given a thorough consultation with your practitioner who will be able to answer any questions that you may have. They will walk you through the procedure and provide the advised number of treatments. A medical history will be taken and you may be asked to sign a consent form. Â Since it is a longer procedure, it is not often performed on the same day as the consultation.
Is there any preparation needed for my polynucleotide treatment?
- Avoid NSAIDs, fish oils and alcohol before your appointment to reduce chances of bruising.
- Ideally arrive at your appointment without make-up, but don’t worry too much if you don’t as your practitioner will thoroughly cleanse the skin before carrying out the treatment.
- Numbing cream will be provided to apply 15 minutes before your treatment
How does this treatment differ from other skin treatments like Profhilo?
Polynucleotide treatments offer not just hydration but also stimulate collagen and elastin, providing a more holistic approach to skin rejuvenation.
Who are the ideal candidates for Polynucleotide Treatment?
Almost anyone can be a candidate for this treatment, with exceptions for those with fish allergies, vegetarians, vegans, or those who are pregnant or breastfeeding.
What does the treatment process involve?
Typically, the treatment requires 2-3 sessions, each spaced about two weeks apart. We also apply a local anaesthetic cream for your comfort during the treatment.
How quickly will I see results and how long will they last?
You can expect to see results soon after the first session. These improvements generally last for about six months.
Are there any risks involved?
As with any injectable treatment, there are some minor risks such as bruising and swelling.